Jarrow Glucosamine + Chondroitin
Glucosamine Sulfate is an essential component of joints and intestinal tissue and is involved in the production of synovial fluid, which lubricates the joints. Sulfur is also utilized in the production of cartilage tissue. A 6-month double-blind, multicenter trial has been recently performed to assess the efficacy of glucosamine sulfate 1500 mg once daily compared to placebo and acetaminophen in patients with osteoarthritis of the knee (GUIDE study). The results showed that glucosamine sulfate improved the Lequesne algofunctional index significantly compared to placebo and the positive control. Secondary analyses, including the OARSI responder indices, were also significantly favorable for glucosamine sulfate. Chondroitin Sulfate stimulates the synthesis of hyaluronic acid which is the lubricant for joints as well as a major component of connective tissue in the skin. The benefit of chondroitin sulfate in patients with osteoarthritis is likely the result of a number of effects including its anti-inflammatory activity, the stimulation of the synthesis of proteoglycans and hyaluronic acid, and the decrease in catabolic activity of chondrocytes inhibiting the synthesis of proteolytic enzymes, nitric oxide and other substances that contribute to damage cartilage matrix and cause death of articular chondrocytes. Chondroitin sulfate has recently shown a positive effect on osteoarthritic structural changes occurred in the subchondral bone. Vitamin C and Manganese are required for the synthesis of collagen and cartilage. For best results, use with Biosil, containing the biologically active form of silicon. These statements have not been evaluated by the food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. SUPPLEMENT FACTS Serving Size 4 Capsules Amount % DV Vitamin C (Ascorbic Acid) 60 mg 100% Manganese (as manganese gluconate) 1 mg 50% Glucosamine Sulfate · 2 KCL 2000 mg * Yielding: Glucosamine Sulfate 1500 mg Potassium Chloride 500 mg Chondroitin Sulfate (from 1333 mg Chondroitin Sulfate Sodium) 1200 mg * * Daily Value not established. Suggested Usage: Take 4 capsules per day, or as directed by your qualified health care consultant. NOTE: DO NOT use if allergic to shellfish. Other Ingredients: Cellulose, magnesium stearate (vegetable source) and silicon dioxide. Capsule consists of gelatin. Contains: Shellfish (shrimp shell). No wheat, no gluten, no soybeans, no dairy, no egg, no fish, no peanuts/tree nuts.
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